It has been suggested that environmental factors play an important role in the onset of AD. CR is believed to counter the effects of aging or brain damage. Ĭognitive Reserve (CR) is a concept based on the plasticity of the brain. Moreover, MoCA is not only highly sensitive in identifying patients with AD, but also non-AD patients who demonstrate behavioral variants of frontotemporal dementia, dementia associated with Parkinson’s disease, and vascular dementia. Previous studies have indicated that the MoCA exhibits high sensitivity and specificity in other languages as well. MoCA has shown higher sensitivity in detecting cognitive decline than the Mini-Mental State Examination (MMSE), another common clinical screening tool for Alzheimer’s disease (AD). The Montreal Cognitive Assessment (MoCA) is known to distinguish patients with Mild Cognitive Impairment (MCI) from the normal population. Therefore, the development and standardization of effective screening tools are required. This increase emphasizes the importance of early detection and treatment of dementia. In recent years, the number of patients with dementia has increased worldwide. Therefore, we suggest that MoCA can be used to assess CR and early cognitive decline. In this study, we show that the MoCA score reflects CR more sensitively than the MMSE score. The MoCA differed from the MMSE in the reflection of total CRI ( Z = 2.30). Correlation and regression analyses of the MoCA, MMSE and CRIq scores were performed, and the MoCA score was compared with the MMSE score to evaluate the degree to which the MoCA reflected CR. Normative data and associated factors of the MoCA were identified. MoCA, MMSE, and the Cognitive Reserve Index questionnaire (CRIq) were administered to 221 healthy participants. Furthermore, we assessed whether there were any differences in the efficacy between the MoCA and the Mini-Mental State Examination (MMSE) in reflecting CR. We aimed to assess whether the MoCA reflects CR. Recently Cognitive Reserve (CR) has been introduced as a factor that compensates cognitive decline. The Montreal Cognitive Assessment (MoCA) is known to have discriminative power for patients with Mild Cognitive Impairment (MCI).

Moca cognitive assessment population